1. Morrone, S.M., Wang, T., Constantoulakis, L.M., Hooy, R.M., Delannoy, M.R., and Sohn, J. (2014) Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy.  PNAS 111, E62-71
  2. Geertsma, H.J., Schute, A.C., Spenkelink, L.M., Mcgrath, W.J., Morrone, S.R., Sohn, J., Mangel, W.F., Robinson, A., van Oijen, (2015) A. Single-molecule imaging at high fluorophore concentrations of Dye (LaDYe). Biophysical Journal 108, 949-56
  3. Baer, A.N., Petri, M.A., Sohn, J., Rosen, A., Casciola-Rosen, L. Antibodies to human IFI16 are present in systemic lupus and primary Sjögren’s syndrome with similar frequencies but detect different parts of molecule. (2015) Arthritis Care Res.
  4. Morrone, S.M., Matyszewski, M., Yu, X., Delannoy, M., Egelman, E.H., and Sohn J. Assembly driven activation of the AIM2 inflammasome provides a template for the polymerization of downstream ASC. (2015) Nature Communications. 6, 7827.
  5. Stratmann, S., Morrone, S.M., van Oijen, A.M.*, and Sohn, J*. The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex. (2015). eLife e11721
  6. Sohn J.* and Hur, S.* Filament assemblies in foreign nucleic acid sensors (2016) Curr Op. Struct. Bio.  37, 134-44.  *: co-corresponding authors.
  7. Matyszewski, M., Morrone, S.M., and Sohn J. Digital signaling network drives the assembly of the AIM2-ASC inflammasome. (2018). PNAS 115: E1963-72
  8. Antiochos, B., Matyszewski, M., Sohn J., Casciola-Rosen, L., and Rosen, A. IFI16 filament formation in salivary epithelial cells shapes the anti-IFI16 immune response in Sjögren’s Syndrome. Journal of Clinical Investigation, Insight. (2018) 3(18)
  9. Hooy, R.M. and Sohn, J. The allosteric activation of cGAS underpins its dynamic signaling landscape. (2018) eLife e39984
  10. Matyszewski, M., Zheng, W., Lueck, J., Antiochos, B, Egelman, E*., and Sohn, J*., The cryo-EM structure of the NLRC4CARD filament provides insights into how symmetric and asymmetric assemblies are utilized in inflammasome signaling. (2018) Journal of Biological Chemistry (2018) *: co-corresponding authors.
  11. DNA sensors and Inflammasomes, Sohn J*. et al. Methods in Enzymology Vol. 625 (2019) *: volume editor and three chapters.
  12. Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death. Jiang H, Xue X, Panda S, Kawale A, Hooy RM, Liang F, Sohn J, Sung P, Gekara NO. EMBO J. 2019 Oct 4;38(21):e102718.
  13. Crews DC*, Wilson KL*, Sohn J*, et al. Helping Scholars Overcome Socioeconomic Barriers to Medical and Biomedical Careers: Creating a Pipeline Initiative (2020). Teach Learn Med. 2020;1-12. *Role: co-first author
  14. Hooy R.M., Massaccesi G, Rousseau K.E., Chattergoon M.A., Sohn J. Allosteric coupling between Mn2+ and dsDNA controls the catalytic efficiency and fidelity of cGAS. (2020) Nucleic Acids Res. gkaa084. PMID: 32170294.
  15. Matyszewski, M., Zheng, W., Lueck, J., Mazanek, Z., Mohideen, N., Lau, A.Y., Egelman, E.H., and Sohn J. Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome. (2021) Nature Communications. In-press